Jejunal disaccharidases in protein energy malnutrition and recovery.

نویسندگان

  • R Mehra
  • S M Khambadkone
  • M K Jain
  • S Ganapathy
چکیده

The jejunal disaccharidases, sucrase, maltase and lactase, were determined in jejunal biopsies obtained from 43 malnourished children and 10 controls. In the study group, 63% were girls and 93% had severe malnutrition. Lactase activity was significantly reduced in third and fourth degree malnutrition (p < 0.05 and p < 0.005, respectively), but maltase activity was significantly reduced only in the fourth degree malnutrition (p < 0.01). After recovery, maltase and sucrase activities showed a marginally significant increase (p = 0.06), where lactase showed no significant increase (p > 0.05). We conclude that jejunal disaccharidase activity decreases significantly with increasing severity of malnutrition, lactase being the most severely affected and the last to recover.

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عنوان ژورنال:
  • Indian pediatrics

دوره 31 11  شماره 

صفحات  -

تاریخ انتشار 1994